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731 Interim results of a multiple ascending dose study of R1626, a novel nucleoside analog targeting hcv polymerase in chronic HCV patients

S. Roberts, Graham Cooksley, David Shaw et al. · Journal of Hepatology · 2006 · 46 citations

Medicine, Infectious Diseases, Pharmacology +14

Down-regulation of the pharmacokinetic-pharmacodynamic response to interleukin-12 during long-term administration to patients with renal cell carcinoma and evaluation of the mechanism of this “adaptive response” in mice

Ashok Rakhit, MyeongHoon Yeon, Jeanne M. Ferrante et al. · Clinical Pharmacology & Therapeutics · 1999 · 43 citations

Medicine, Oncology, Pharmacology +17

A phase Ib dose-escalation study of erlotinib, capecitabine and oxaliplatin in metastatic colorectal cancer patients

Eric Van Cutsem, Chris Verslype, Philip Beale et al. · Annals of Oncology · 2007 · 36 citations

Medicine, Oncology, Pharmacology +14

A phase 1b dose-escalation trial of erlotinib, capecitabine and oxaliplatin in metastatic colorectal cancer (MCRC) patients

J.P. Delord, Philip Beale, Eric Van Cutsem et al. · Journal of Clinical Oncology · 2004 · 21 citations

Medicine, Pharmacokinetics, Pharmacology +17