Establishment and Characterization of a Steroidogenic Human Granulosa-Like Tumor Cell Line, KGN, That Expresses Functional Follicle-Stimulating Hormone Receptor

Yoshihiro Nishi, Toshihiko Yanase, MU Yi-ming, +11

Endocrinology

Steroid MetabolismA Steroid AnalysisHormonal ReceptorAbnormal KaryotypeGynecology +9

Saturated FFAs, Palmitic Acid and Stearic Acid, Induce Apoptosis in Human Granulosa Cells

Yi-Ming Mu, Toshihiko Yanase, Yoshihiro Nishi, +8

Endocrinology

Lipid PeroxidationApoptosisCell DeathCellular PhysiologyInsulin Signaling +21

Androgen Receptor Null Male Mice Develop Late-Onset Obesity Caused by Decreased Energy Expenditure and Lipolytic Activity but Show Normal Insulin Sensitivity With High Adiponectin Secretion

WuQiang Fan, Toshihiko Yanase, Masatoshi Nomura, +6

Diabetes

Androgen-Insensitivity Syndrome as a Possible Coactivator Disease

Masahiro Adachi, Ryoichi Takayanagi, Arihiro Tomura, +6

New England Journal of Medicine

Androgen ReceptorGeneticsGynecologyFemale Reproductive FunctionReproductive Biology +19

Tributyltin or Triphenyltin Inhibits Aromatase Activity in the Human Granulosa-like Tumor Cell Line KGN

Masayuki Saitoh, Toshihiko Yanase, Hidetaka Morinaga, +8

Biochemical and Biophysical Research Communications

BiochemistryOncogenic AgentMedicineAromataseAnti-cancer Agent +5

The Subnuclear Three-dimensional Image Analysis of Androgen Receptor Fused to Green Fluorescence Protein

Arihiro Tomura, Kiminobu Goto, Hidetaka Morinaga, +5

Journal of Biological Chemistry

Androgen ReceptorMolecular BiologyGreen Fluorescence ProteinTranscriptional RegulationActive Androgen Receptor +16

A Benzimidazole Fungicide, Benomyl, and Its Metabolite, Carbendazim, Induce Aromatase Activity in a Human Ovarian Granulose-Like Tumor Cell Line (KGN)

Hidetaka Morinaga, Toshihiko Yanase, Masatoshi Nomura, +4

Endocrinology

Secondary MetaboliteOvarian CancerAnti-cancer AgentMicrotubule-interfering MechanismBiochemistry +15

Activation of Peroxisome Proliferator-Activated Receptor-γ and Retinoid X Receptor Inhibits Aromatase Transcription via Nuclear Factor-κB

WuQiang Fan, Toshihiko Yanase, Hidetaka Morinaga, +6

Endocrinology

Aromatase Promoter IiAromatase ActivityAromatase GeneOvarian CancerTranscriptional Regulation +15

Cloning of the Sequences Expressed Abundantly in Established Cell Lines: Identification of a cDNA Clone Highly Homologous to S-100, a Calcium Binding Protein1

Kiminobu Goto, Hideya Endo, Toshinobu Fujiyoshi

The Journal of Biochemistry

Combined treatment with specific ligands for PPARγ:RXR nuclear receptor system markedly inhibits the expression of cytochrome P450arom in human granulosa cancer cells

Yi-Ming Mu, Toshihiko Yanase, Yoshihiro Nishi, +3

Molecular and Cellular Endocrinology

Specific LigandsMolecular PharmacologyMedicinePharmacologyCancer Cell Biology +7