Jian-Sung Wu

Protein Kinase Inhibitor Design by Targeting the Asp-Phe-Gly (DFG) Motif: The Role of the DFG Motif in the Design of Epidermal Growth Factor Receptor Inhibitors

Yi-Hui Peng, Hui-Yi Shiao, Chih‐Hsiang Tu et al. · Journal of Medicinal Chemistry · 2013 · 135 citations · Full text

Drug Target, Medicinal Chemistry, Signaling Pathway +18

Scaffold-Hopping Strategy: Synthesis and Biological Evaluation of 5,6-Fused Bicyclic Heteroaromatics To Identify Orally Bioavailable Anticancer Agents

Yen-Shih Tung, Mohane Selvaraj Coumar, Yu-Shan Wu et al. · Journal of Medicinal Chemistry · 2011 · 95 citations

Combinatorial Chemistry, Medicinal Chemistry, Scaffold-hopping Strategy +13

5-Amino-2-Aroylquinolines as Highly Potent Tubulin Polymerization Inhibitors

Chih-Ying Nien, Yun-Ching Chen, Ching‐Chuan Kuo et al. · Journal of Medicinal Chemistry · 2010 · 75 citations

Structure-Based Drug Design of Novel Aurora Kinase A Inhibitors: Structural Basis for Potency and Specificity

Mohane Selvaraj Coumar, Jiun-Shyang Leou, Paritosh Shukla et al. · Journal of Medicinal Chemistry · 2009 · 74 citations · Full text

Phenyl Benzenesulfonylhydrazides Exhibit Selective Indoleamine 2,3-Dioxygenase Inhibition with Potent <i>in Vivo</i> Pharmacodynamic Activity and Antitumor Efficacy

Shu‐Yu Lin, Teng-Kuang Yeh, Ching‐Chuan Kuo et al. · Journal of Medicinal Chemistry · 2015 · 73 citations · Full text

Tryptophan Metabolism, Medicinal Chemistry, Biochemistry +12