Activity of the Novel Dual Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Inhibitor NVP-BEZ235 against T-Cell Acute Lymphoblastic Leukemia

Francesca Chiarini, Cecilia Grimaldi, Francesca Ricci, +10

Cancer Research

Pi3k/akt/mtor NetworkMixed-phenotype Acute LeukemiaImmunologyImmunotherapyTumor Biology +14

An Italian national multicenter study for the definition of reference ranges for normal values of peripheral blood lymphocyte subsets in healthy adults.

Alberto Santagostino, G Garbaccio, Angela Pistorio, +4

PubMed

ImmunologyBlood CellImmunophenotypingImmunotherapyLaboratory Hematology +16

Dual Inhibition of Class IA Phosphatidylinositol 3-Kinase and Mammalian Target of Rapamycin as a New Therapeutic Option for T-Cell Acute Lymphoblastic Leukemia

Francesca Chiarini, Federica Falà, Pier Luigi Tazzari, +6

Cancer Research

Mixed-phenotype Acute LeukemiaImmunologyNew Therapeutic OptionCell DeathClass Ia Phosphatidylinositol +18

Identification of TLR4 as the Receptor That Recognizes Shiga Toxins in Human Neutrophils

Maurizio Brigotti, Domenica Carnicelli, Valentina Arfilli, +8

The Journal of Immunology

Clinical Relevance of Shiga Toxin Concentrations in the Blood of Patients With Hemolytic Uremic Syndrome

Maurizio Brigotti, Pier Luigi Tazzari, Elisa Ravanelli, +14

The Pediatric Infectious Disease Journal

Harnessing the PI3K/Akt/mTOR pathway in T-cell acute lymphoblastic leukemia: Eliminating activity by targeting at different levels

Daniela Bressanin, Camilla Evangelisti, Francesca Ricci, +9

Oncotarget

Multidistrict human mesenchymal vascular cells: pluripotency and stemness characteristics

Gianandrea Pasquinelli, Annalisa Pacilli, Francesco Alviano, +10

Cytotherapy

Regenerative MedicineMedicineAdult Stem CellStem Cell ResearchBiomedical Engineering +3

Preclinical testing of the Akt inhibitor triciribine in T‐cell acute lymphoblastic leukemia

Camilla Evangelisti, Francesca Ricci, Pier Luigi Tazzari, +8

Journal of Cellular Physiology

Pi3k InhibitorsApoptosisImmunologyCell DeathPharmacotherapy +20

Neutrophil Gelatinase-Associated Lipocalin Increases HLA-G+/FoxP3+ T-Regulatory Cell Population in an In Vitro Model of PBMC

Gaetano La Manna, Giulia Ghinatti, Pier Luigi Tazzari, +9

PLoS ONE

A combination of temsirolimus, an allosteric mTOR inhibitor, with clofarabine as a new therapeutic option for patients with acute myeloid leukemia

Francesca Chiarini, Annalisa Lonetti, Gabriella Teti, +13

Oncotarget