Hypoxia-induced VEGF and collagen I expressions are associated with angiogenesis and fibrogenesis in experimental cirrhosis

Christophe Corpechot, Véronique Barbu, Dominique Wendum, +5

Hepatology

Liver FibrosisPathologyCholangiopathiesCirrhosisAngiogenesis +21

Mechanical induction of the tumorigenic β-catenin pathway by tumour growth pressure

María Elena Fernández-Sánchez, Sandrine Barbier, Joanne Whitehead, +19

Nature

MechanobiologyTumorigenic β-Catenin PathwayTumour Growth PressureMechanical InductionCell-matrix Interaction +8

Gefitinib, an EGFR inhibitor, prevents hepatocellular carcinoma development in the rat liver with cirrhosis†

Eduardo Schiffer, Chantal Housset, Wulfran Cacheux, +7

Hepatology

PathologyGrowth Factor AlphaTumor BiologyCirrhosisOncology +18

Cellular localization of endothelin-1 and increased production in liver injury in the rat: Potential for autocrine and paracrine effects on stellate cells

Don C. Rockey, Laura Fouassier, John J. Chung, +4

Hepatology

The Myofibroblastic Conversion of Peribiliary Fibrogenic Cells Distinct from Hepatic Stellate Cells Is Stimulated by Platelet-Derived Growth Factor During Liver Fibrogenesis

Nils Kinnman, Claire Francoz, Véronique Barbu, +5

Laboratory Investigation

Liver FibrogenesisFibrosisDevelopmental BiologyHepatologyPlatelet-derived Growth Factor +12

Epidermal growth factor receptor and HER-3 restrict cell response to sorafenib in hepatocellular carcinoma cells

Marie-José Blivet-Van Eggelpoël, Hamza Chettouh, Lynda Aoudjehane, +6

Journal of Hepatology

Hepatocellular CarcinomaMedicineLiver PhysiologyHepatocellular Carcinoma CellsPathology +5

Prominent contribution of portal mesenchymal cells to liver fibrosis in ischemic and obstructive cholestatic injuries

Marc Beaussier, Dominique Wendum, Eduardo Schiffer, +4

Laboratory Investigation

PathologyCholangiopathiesCirrhosisRegenerative MedicineInflammation +18

PDGF-Mediated Chemoattraction of Hepatic Stellate Cells by Bile Duct Segments in Cholestatic Liver Injury

Nils Kinnman, Rolf Hultcrantz, Véronique Barbu, +4

Laboratory Investigation

HepatologyBile Duct SegmentsHepatic Stellate CellsBiliary TractLiver Physiology +11

Mitogenic Insulin Receptor-A Is Overexpressed in Human Hepatocellular Carcinoma due to EGFR-Mediated Dysregulation of RNA Splicing Factors

Hamza Chettouh, Lynda Aoudjehane, Dominique Wendum, +10

Cancer Research

Egfr-mediated DysregulationHuman Hepatocellular CarcinomaPathologyInsulin ReceptorInsulin Signaling +17

Portal myofibroblasts promote vascular remodeling underlying cirrhosis formation through the release of microparticles

Sara Lemoinne, Axelle Cadoret, Pierre‐Emmanuel Rautou, +12

Hepatology