John Simes

Effect of Laparoscopic-Assisted Resection vs Open Resection on Pathological Outcomes in Rectal Cancer

Andrew R. L. Stevenson, Michael J. Solomon, John W. Lumley et al. · JAMA · 2015 · 1K citations · Full text

Medicine, Oncology, Surgery +17

Association of KRAS p.G13D Mutation With Outcome in Patients With Chemotherapy-Refractory Metastatic Colorectal Cancer Treated With Cetuximab

Wendy De Roock, Derek J. Jonker, Federica Di Nicolantonio et al. · JAMA · 2010 · 747 citations

Medicine, Oncology, Pharmacology +17

Cost Effectiveness of Thrombolytic Therapy with Tissue Plasminogen Activator as Compared with Streptokinase for Acute Myocardial Infarction

Daniel B. Mark, Mark A. Hlatky, Robert M. Califf et al. · New England Journal of Medicine · 1995 · 524 citations · Full text

Medicine, Cardiology, Pharmacoeconomics +14

Comparison of two doses of imatinib for the treatment of unresectable or metastatic gastrointestinal stromal tumors (GIST): A meta-analyis based on 1,640 patients (pts)

M. M. Van Glabbeke, Kouros Owzar, Cathryn Rankin et al. · Journal of Clinical Oncology · 2007 · 383 citations

Medicine, Oncology, Pharmacology +10

Guidelines for Reporting Trial Protocols and Completed Trials Modified Due to the COVID-19 Pandemic and Other Extenuating Circumstances

Aaron Orkin, Peter Gill, Davina Ghersi et al. · JAMA · 2021 · 313 citations · Full text

Public Health, Internal Medicine, Clinical Research Regulation +16