Peter M. Finan

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

Jordi Barretina, Giordano Caponigro, Nicolas Stransky et al. · Nature · 2012 · 8.3K citations

Tumor Biology, Predictive Modelling, Drug Target +12

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

Shih-Min A. Huang, Yuji Mishina, Shanming Liu et al. · Nature · 2009 · 2.1K citations

Tankyrase Inhibition, Signal Transduction, Signaling Pathway +7

Activation of a Metabolic Gene Regulatory Network Downstream of mTOR Complex 1

Katrin Düvel, Jessica L. Yecies, Suchithra Menon et al. · Molecular Cell · 2010 · 1.9K citations · Full text

Metabolic Network, Systems Biology, Signal Transduction +9

Bidirectional Transport of Amino Acids Regulates mTOR and Autophagy

Paul Nicklin, Philip J. Bergman, Bailin Zhang et al. · Cell · 2009 · 1.7K citations · Full text

Cell Autophagy, Mitophagy, Signal Transduction +8

COT drives resistance to RAF inhibition through MAP kinase pathway reactivation

Cory M. Johannessen, Jesse S. Boehm, So Young Kim et al. · Nature · 2010 · 1.4K citations · Full text

Signal Transduction, Signaling Pathway, Molecular Pathway +9