Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53

Hiroshi Katayama, Kaori Sasai, Hidehiko Kawai, +7

Nature Genetics

Signal TransductionSignaling PathwayAurora KinaseCell RegulationMedicine +9

DNA Damage-induced MDMX Degradation Is Mediated by MDM2

Hidehiko Kawai, Dmitri Wiederschain, Hiroyuki Kitao, +3

Journal of Biological Chemistry

ZBTB7A acts as a tumor suppressor through the transcriptional repression of glycolysis

Xuesong Liu, Jenna E. Haines, Elie K. Mehanna, +5

Genes & Development

Activation of MEK Kinase 1 by the c-Abl Protein Tyrosine Kinase in Response to DNA Damage

Surender Kharbanda, Pramod S. Pandey, Teruo Yamauchi, +10

Molecular and Cellular Biology

A phosphotyrosine switch determines the antitumor activity of ERβ

Bin Yuan, Long Cheng, Huai-Chin Chiang, +16

Journal of Clinical Investigation

Low-Dose Radiation-Induced Senescent Stromal Fibroblasts Render Nearby Breast Cancer Cells Radioresistant

Kelvin K. Tsai, Jeremy Stuart, Yao-Yu Eric Chuang, +2

Radiation Research

Radiation OncologyRadiation MedicineBreast OncologyRadiation TherapyCarcinoma Cells +11

Regulation of Ionizing Radiation-induced Rad52 Nuclear Foci Formation by c-Abl-mediated Phosphorylation

Hiroyuki Kitao, Zhi-Min Yuan

Journal of Biological Chemistry

Function for p300 and not CBP in the apoptotic response to DNA damage

Zhi-Min Yuan, Yinyin Huang, Takatoshi Ishiko, +7

Oncogene

Genome InstabilityDna DamageApoptosisApoptotic ResponseMolecular Biology +4

Functional role for the c-Abl tyrosine kinase in meiosis I

Surender Kharbanda, Pramod S. Pandey, Patricia L. Morris, +10

Oncogene

Signal TransductionCell RegulationCell DivisionCell SignalingReceptor Tyrosine Kinase +8

ZBTB7A Suppresses Melanoma Metastasis by Transcriptionally Repressing MCAM

Xuesong Liu, Matthew Genet, Jenna E. Haines, +10

Molecular Cancer Research