B cell depletion as a novel treatment for systemic lupus erythematosus: A phase I/II dose‐escalation trial of rituximab

R. John Looney, Jennifer H. Anolik, Debbie Campbell, +6

Arthritis & Rheumatism

Diversity, cellular origin and autoreactivity of antibody-secreting cell population expansions in acute systemic lupus erythematosus

Christopher M. Tipton, Christopher Fucile, Jaime Darce, +13

Nature Immunology

ImmunogeneticsCellular OriginAutoimmune DiseaseSystemic Lupus ErythematosusAutoantibody Production +7

Long-Lived Plasma Cells Are Contained within the CD19−CD38hiCD138+ Subset in Human Bone Marrow

Jessica L. Halliley, Christopher M. Tipton, Jane L. Liesveld, +21

Immunity

Human CellMedicineImmunologyHematologyBlood Cell +6

Rituximab improves peripheral B cell abnormalities in human systemic lupus erythematosus

Jennifer H. Anolik, Jennifer Barnard, Amedeo Cappione, +4

Arthritis & Rheumatism

Digestion of Chromatin in Apoptotic Cell Microparticles Prevents Autoimmunity

Vanja Sisirak, Benjamin Sally, Vivette D. D’Agati, +18

Cell

ChromatinAutoimmune DiseaseAutoantibody ProductionChromatin RemodelingImmunology +3

The relationship of FcγRIIIa genotype to degree of B cell depletion by rituximab in the treatment of systemic lupus erythematosus

Jennifer H. Anolik, Debbie Campbell, Raymond E. Felgar, +4

Arthritis & Rheumatism

Regulation of inherently autoreactive VH4-34 B cells in the maintenance of human B cell tolerance

Aimee E. Pugh‐Bernard, Gregg J. Silverman, Amedeo Cappione, +4

Journal of Clinical Investigation

Adaptive Immune SystemImmunologyImmunotherapyImmune DysregulationImmunogenetics +14

Regulation of inherently autoreactive VH4-34 B cells in the maintenance of human B cell tolerance

Aimee E. Pugh‐Bernard, Gregg J. Silverman, Amedeo Cappione, +4

Journal of Clinical Investigation

Adaptive Immune SystemImmunologyImmunotherapyImmune DysregulationImmunogenetics +14

Germinal center exclusion of autoreactive B cells is defective in human systemic lupus erythematosus

Amedeo Cappione, Jennifer H. Anolik, Aimee E. Pugh‐Bernard, +4

Journal of Clinical Investigation

Defective Tolerance CheckpointHumoral ResponseImmunologyB Cell TolerancePathology +16

Malaria-associated atypical memory B cells exhibit markedly reduced B cell receptor signaling and effector function

Sílvia Portugal, Christopher M. Tipton, Haewon Sohn, +15

eLife

Autoimmune DiseaseEffector FunctionPathogenesisImmunologyMalaria +10