Analysis of interleukin-1α (IL-1α) and interleukin-8 (IL-8) expression and release in in vitro reconstructed human epidermis for the prediction of in vivo skin irritation and/or sensitization

Alain Coquette, Nancy Berna, A. Vandenbosch, +3

Toxicology in Vitro

InflammationCutaneous BiologyImmune RegulationImmunologyHuman Epidermis +7

Differential Expression of Extracellular Matrix Metalloproteinase Inducer (CD147) in Normal and Ulcerated Corneas

Éric Gabison, Samia Mourah, Emanuelle Steinfels, +7

American Journal Of Pathology

InflammationOphthalmologyDifferential ExpressionUlcerated CorneasPathology +7

Assessment of the human epidermis model SkinEthic RHE for in vitro skin corrosion testing of chemicals according to new OECD TG 431

Helena Kanďárová, Manfred Liebsch, Horst Spielmann, +12

Toxicology in Vitro

Materials ScienceEngineeringCorrosionCutaneous BiologySkin Substitute +5

Prevalidation of a new in vitro reconstituted human cornea model to assess the eye irritating potential of chemicals

Freddy Van Goethem, E. Adriaens, Nathalie Alépée, +7

Toxicology in Vitro

OphthalmologyBiochemistryMedicineExperimental OphthalmologyToxicology +3

Retrospective analysis of the Draize test for serious eye damage/eye irritation: importance of understanding the in vivo endpoints under UN GHS/EU CLP for the development and evaluation of in vitro test methods

Els Adriaens, Chantra Eskes, Sebastian Hoffmann, +8

Archives of Toxicology

Predictivity of an in vitro model for acute and chronic skin irritation (SkinEthic) applied to the testing of topical vehicles

A. de Brugerolle de Fraissinette, Valérie Picarles, Salah‐Dine Chibout, +11

Cell Biology and Toxicology

Transcriptional Profiling of Epidermal Keratinocytes: Comparison of Genes Expressed in Skin, Cultured Keratinocytes, and Reconstituted Epidermis, Using Large DNA Microarrays

Alix Gazel, Patricia Ramphal, Martin Rosdy, +6

Journal of Investigative Dermatology

Skin DevelopmentTranscriptional ProfilingCutaneous BiologyDna MicroarraysEpidermal Keratinocytes +8

Toxicology in the 21st century – Working our way towards a visionary reality

Ninna Berg, Bart De Wever, Horst W. Fuchs, +3

Toxicology in Vitro

Medical ToxicologyToxicology TestingEnvironmental HealthToxicologyToxicological Aspect +14

Assessment of the Skin Irritation Potential of Chemicals by Using the SkinEthic Reconstructed Human Epidermal Model and the Common Skin Irritation Protocol Evaluated in the ECVAM Skin Irritation Validation Study

Helena Kanďárová, Manfred Liebsch, Elisabeth Schmidt, +8

Alternatives to Laboratory Animals

Skin Irritation PotentialAllergyMedicineBioanalysisSkin Allergy +10

Human Skin Models for Research Applications in Pharmacology and Toxicology: Introducing NativeSkin ^® , the “Missing Link” Bridging Cell Culture and/or Reconstructed Skin Models and Human Clinical Testing

Bart De Wever, Sandrine Kurdykowski, Pascal Descargues

Applied In Vitro Toxicology