R D Christen

The role of DNA mismatch repair in platinum drug resistance.

Daniel Fink, S Nebel, Stefan Aebi et al. · PubMed · 1996 · 603 citations

Dna Damage, Genetics, Dna Analysis +18

Loss of DNA mismatch repair in acquired resistance to cisplatin.

Stefan Aebi, Buran Kurdi-Haidar, Robert T. Gordon et al. · PubMed · 1996 · 504 citations

Genome Instability, Somatic Variant, Genetics +10

CSF1R inhibition with emactuzumab in locally advanced diffuse-type tenosynovial giant cell tumours of the soft tissue: a dose-escalation and dose-expansion phase 1 study

Philippe A. Cassier, Antoîne Italiano, Carlos Gomez-Roca et al. · The Lancet Oncology · 2015 · 356 citations

Medicine, Immunology, Pathology +9

In vitro and in vivo resistance to cisplatin in cells that have lost DNA mismatch repair.

Daniel Fink, Hongtu Zheng, S Nebel et al. · PubMed · 1997 · 278 citations

Cisplatin Resistance, Chromatin, Genome Instability +13

Phase I study of emactuzumab single agent or in combination with paclitaxel in patients with advanced/metastatic solid tumors reveals depletion of immunosuppressive M2-like macrophages

C. Gomez-Roca, Antoîne Italiano, Christophe Le Tourneau et al. · Annals of Oncology · 2019 · 189 citations · Full text

Immunosuppressive M2-like Macrophages, Medicine, Metronomic Therapy +6