Takefumi Shimizu

The Uracil Breath Test in the Assessment of Dihydropyrimidine Dehydrogenase Activity: Pharmacokinetic Relationship between Expired 13CO2 and Plasma [2-13C]Dihydrouracil

Lori K. Mattison, Jeanne Fourie, Yukihiro Hirao et al. · Clinical Cancer Research · 2006 · 76 citations

Pharmacy, Pharmacokinetics, Pharmacology +13

Comparison of Inducibility of CYP1A and CYP3A mRNAs by Prototypical Inducers in Primary Cultures of Human, Cynomolgus Monkey, and Rat Hepatocytes

Masuhiro Nishimura, Akiko Koeda, Yasuyuki Suganuma et al. · Drug Metabolism and Pharmacokinetics · 2007 · 71 citations

Medicine, Biochemistry, Molecular Biology +11

Studies on 2-oxoquinoline derivatives as blood platelet aggregation inhibitors. II. 6-(3-(1-Cyclohexyl-5-tetrazolyl)propoxy)-1,2-dihydro-2-oxoquinoline and related compounds.

Takao Nishi, Fujio Tabusa, Tatsuyoshi Tanaka et al. · Chemical and Pharmaceutical Bulletin · 1983 · 60 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Effects of prototypical drug-metabolizing enzyme inducers on mRNA expression of housekeeping genes in primary cultures of human and rat hepatocytes

Masuhiro Nishimura, Akiko Koeda, Emako Suzuki et al. · Biochemical and Biophysical Research Communications · 2006 · 35 citations

Medicine, Biochemistry, Pharmacology +17

Studies on 2-oxoquinoline derivatives as blood platelet aggregation inhibitors. IV. Synthesis and biological activity of the metabolites of 6-(4-(1-cyclohexyl-1H-5-tetrazolyl)butoxy)-2-oxo-1,2,3,4-tetrahydroquinoline(OPC-13013).

Takao Nishi, Fujio Tabusa, Tatsuyoshi Tanaka et al. · Chemical and Pharmaceutical Bulletin · 1985 · 31 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15