Armin Kern

Discovery of the Soluble Guanylate Cyclase Stimulator Vericiguat (BAY 1021189) for the Treatment of Chronic Heart Failure

Markus Follmann, Jens Ackerstaff, Gorden Redlich et al. · Journal of Medicinal Chemistry · 2017 · 189 citations · Full text

Medicinal Chemistry, Heart Failure, Chronic Heart Failure +15

Discovery of Riociguat (BAY 63‐2521): A Potent, Oral Stimulator of Soluble Guanylate Cyclase for the Treatment of Pulmonary Hypertension

Joachim Mittendorf, Stefan Weigand, Cristina Alonso‐Alija et al. · ChemMedChem · 2009 · 180 citations

Molecular Pharmacology, Pulmonary Arterial Hypertension, Biochemistry +14

Rhizocticin A, an antifungal phosphono-oligopeptide of Bacillus subtilis ATCC 6633: biological properties

M. Kugler, W. Loeffler, Claudius Rapp et al. · Archives of Microbiology · 1990 · 125 citations

Antifungal Agent, Biochemistry, Bacteriology +5

Metabolism of cerivastatin by human liver microsomes in vitro. Characterization of primary metabolic pathways and of cytochrome P450 isozymes involved.

Michael Boberg, Rolf Angerbauer, Peter Fey et al. · PubMed · 1997 · 77 citations

Metabolomic Profiling, Primary Metabolic Pathways, Cerivastatin Metabolism +19

Discovery of the Soluble Guanylate Cyclase Activator Runcaciguat (BAY 1101042)

Michael G. Hahn, Thomas Lampe, Sherif El Sheikh et al. · Journal of Medicinal Chemistry · 2021 · 57 citations · Full text