Elliott Sigal

The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding

John N. Feder, David M. Penny, Alivelu Irrinki et al. · Proceedings of the National Academy of Sciences · 1998 · 837 citations · Full text

Histocompatibility, Gene Product, Signal Transduction +15

The structure of mammalian 15-lipoxygenase reveals similarity to the lipases and the determinants of substrate specificity

S.A. Gillmor, Armando G. Villaseñor, Robert J. Fletterick et al. · Nature Structural Biology · 1997 · 448 citations

Biochemistry, Natural Sciences, Substrate Specificity +4

Colocalization of 15-lipoxygenase mRNA and protein with epitopes of oxidized low density lipoprotein in macrophage-rich areas of atherosclerotic lesions.

Seppo Ylä‐Herttuala, Margaret Rosenfeld, S Parthasarathy et al. · Proceedings of the National Academy of Sciences · 1990 · 427 citations · Full text

Lipid Peroxidation, Immunology, Pathology +18

Specific inflammatory cytokines regulate the expression of human monocyte 15-lipoxygenase.

Douglas Conrad, Hartmut Kühn, Mary A. Mulkins et al. · Proceedings of the National Academy of Sciences · 1992 · 383 citations · Full text

Lipid Peroxidation, Immunology, Redox Biology +18

Gene expression in macrophage-rich human atherosclerotic lesions. 15-lipoxygenase and acetyl low density lipoprotein receptor messenger RNA colocalize with oxidation specific lipid-protein adducts.

Seppo Ylä‐Herttuala, Michael E. Rosenfeld, Srinivasan Parthasarathy et al. · Journal of Clinical Investigation · 1991 · 380 citations · Full text

Lipid Peroxidation, Immunology, Pathology +19