Jorge Vialard

Convergent Mutations and Kinase Fusions Lead to Oncogenic STAT3 Activation in Anaplastic Large Cell Lymphoma

Ramona Crescenzo, Francesco Abate, Elena Lasorsa et al. · Cancer Cell · 2015 · 429 citations · Full text

Lymphoid Neoplasia, Medicine, Convergent Mutations +8

Discovery and Pharmacological Characterization of JNJ-42756493 (Erdafitinib), a Functionally Selective Small-Molecule FGFR Family Inhibitor

Timothy Perera, Eleonora Jovcheva, Laurence Mévellec et al. · Molecular Cancer Therapeutics · 2017 · 335 citations · Full text

Human Mus81-Associated Endonuclease Cleaves Holliday Junctions In Vitro

Xiaobo Chen, Roberta Melchionna, Cécile‐Marie Aliouat‐Denis et al. · Molecular Cell · 2001 · 260 citations · Full text

Signal Transduction, Endocytic Pathway, Intracellular Trafficking +5

Repurposing High-Throughput Image Assays Enables Biological Activity Prediction for Drug Discovery

Jaak Simm, Günter Klambauer, Ádám Arany et al. · Cell chemical biology · 2018 · 247 citations · Full text

Drug Target, Engineering, Hit Identification +11

Critical Role of the Ubiquitin Ligase Activity of UHRF1, a Nuclear RING Finger Protein, in Tumor Cell Growth

Yonchu Jenkins, Vadim Markovtsov, Wayne Lang et al. · Molecular Biology of the Cell · 2005 · 183 citations · Full text

Chromatin, Tumor Cell Growth, Cell Cycle Checkpoints +15