Nick La Thangue

Pharmacological activation of STAT1-GSDME pyroptotic circuitry reinforces epigenetic immunotherapy for hepatocellular carcinoma

Yalin Tu, Haoran Wu, Chengpeng Zhong et al. · Gut · 2024 · 38 citations · Full text

Medicine, Immunology, Oncology +17

CXD101 and nivolumab in patients with metastatic microsatellite-stable colorectal cancer (CAROSELL): a multicentre, open-label, single-arm, phase II trial

Mark Saunders, Jeffrey Graham, David Cunningham et al. · ESMO Open · 2022 · 32 citations · Full text

Medicine, Immunology, Oncology +17

A phase 1 study to assess the safety, tolerability, and pharmacokinetics of CXD101 in patients with advanced cancer

Toby A. Eyre, Graham P. Collins, Avinash Gupta et al. · Cancer · 2018 · 22 citations · Full text

Pharmacy, Oncology, Pharmacology +13

JMY protein, a regulator of P53 and cytoplasmic actin filaments, is expressed in normal and neoplastic tissues

Omanma Adighibe, Helen Turley, Russell Leek et al. · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin · 2014 · 14 citations

Life Sciences, Cell Biology, Molecular Biology +14