Extra-pleural pneumonectomy versus no extra-pleural pneumonectomy for patients with malignant pleural mesothelioma: clinical outcomes of the Mesothelioma and Radical Surgery (MARS) randomised feasibility study

Tom Treasure, Loı̈c Lang-Lazdunski, David Waller, +15

The Lancet Oncology

Excision Margins in High-Risk Malignant Melanoma

Joseph Thomas, Julia Newton‐Bishop, Roger A’Hern, +9

New England Journal of Medicine

Fulvestrant plus anastrozole or placebo versus exemestane alone after progression on non-steroidal aromatase inhibitors in postmenopausal patients with hormone-receptor-positive locally advanced or metastatic breast cancer (SoFEA): a composite, multicentre, phase 3 randomised trial

Stephen Johnston, Lucy Kilburn, David Dodwell, +17

The Lancet Oncology

Adjuvant cyclophosphamide, methotrexate, and fluorouracil versus fluorouracil, epirubicin, and cyclophosphamide chemotherapy in premenopausal women with axillary node-positive operable breast cancer: results of a randomized trial. The International Collaborative Cancer Group.

R. Charles Coombes, Judith M. Bliss, J. Wils, +15

Journal of Clinical Oncology

Epirubicin Plus Tamoxifen Versus Tamoxifen Alone in Node-Positive Postmenopausal Patients With Breast Cancer: A Randomized Trial of the International Collaborative Cancer Group

J. Wils, Judith M. Bliss, M. Marty, +8

Journal of Clinical Oncology

A novel continuous infusional 5-fluorouracil-based chemotherapy regimen compared with conventional chemotherapy in theneo-adjuvant treatment of early breast cancer: 5 year results of the TOPIC trial

Ian E. Smith, Roger A’Hern, Gill Coombes, +12

Annals of Oncology

Topic TrialConventional ChemotherapyOncologyBreast OncologyEarly Breast Cancer +5

A Quality-of-Life Study in High-Risk (Thickness≥2 mm) Cutaneous Melanoma Patients in a Randomized Trial of 1-cm versus 3-cm Surgical Excision Margins

Julia Newton‐Bishop, Clarissa Nolan, Faye Turner, +6

Journal of Investigative Dermatology Symposium Proceedings

Surgical OncologyMedicineMelanomaOutcomes ResearchSurgery +7

Neoadjuvant vinorelbine/epirubicin (VE) versus standard adriamycin/cyclophosphamide (AC) in operable breast cancer: analysis of response and tolerability in a randomised phase III trial (TOPIC 2)

Susan Chua, Ian E. Smith, Roger A’Hern, +12

Annals of Oncology

Surgical OncologyNeoadjuvant Vinorelbine/epirubicinBreast OncologyMedicineCancer Management +8

Antiproliferative Effect of Lapatinib in HER2-Positive and HER2-Negative/HER3-High Breast Cancer: Results of the Presurgical Randomized MAPLE Trial (CRUK E/06/039)

Alexandra Léary, Abigail Evans, Stephen Johnston, +11

Clinical Cancer Research

2LBA Fulvestrant Alone or with Concomitant Anastrozole Vs Exemestane Following Progression On Non-steroidal Aromatase Inhibitor – First Results of the SoFEa Trial (CRUKE/03/021 & CRUK/09/007) (ISRCTN44195747)

S. Johnston, Lucy Kilburn, Peter Ellis, +7

European Journal of Cancer

Molecular PharmacologySofea TrialPharmacologyFulvestrant AloneSecondary Metabolite +5