Quinoxalinediones: Potent Competitive Non-NMDA Glutamate Receptor Antagonists

Tage Honoré, S.N. Davies, Jørgen Drejer, +4

Science

Synaptic TransmissionNeurotransmitterPharmacotherapyNeurotransmissionGlutamate Receptors +16

2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a Neuroprotectant for Cerebral Ischemia

Malcolm J. Sheardown, Elsebet Ø. Nielsen, Anker Jón Hansen, +2

Science

PharmacotherapyDrug ResistanceBrain InjuryNeurologyIschemic Syndrome +16

Adipose Triglyceride Lipase and Hormone-sensitive Lipase Are the Major Enzymes in Adipose Tissue Triacylglycerol Catabolism

Martina Schweiger, Renate Schreiber, Guenter Haemmerle, +6

Journal of Biological Chemistry

Major EnzymesAdipose LipolysisMetabolic SyndromeFat Cell LipolysisHealth Sciences +15

ZK200775: A phosphonate quinoxalinedione AMPA antagonist for neuroprotection in stroke and trauma

Lechosław Turski, Andreas Huth, Malcolm J. Sheardown, +7

Proceedings of the National Academy of Sciences

Pharmaceutical ScienceBioorganic ChemistryCerebrovascular DiseasePharmacotherapyPharmaceutical Chemistry +25

Adipose triglyceride lipase in human skeletal muscle is upregulated by exercise training

Thomas J. Alsted, Lars Nybo, Martina Schweiger, +5

American Journal of Physiology-Endocrinology and Metabolism

The Critical Role of Neutral Cholesterol Ester Hydrolase 1 in Cholesterol Removal From Human Macrophages

Masaki Igarashi, Jun-ichi Osuga, Hiroshi Uozaki, +18

Circulation Research

Synthesis and Structure−Activity Relationship for a Novel Class of Potent and Selective Carbamoyl-Triazole Based Inhibitors of Hormone Sensitive Lipase

Søren Ebdrup, Lotte G. Sørensen, Ole H. Olsen, +1

Journal of Medicinal Chemistry

Glucose ToleranceMedicinal ChemistryHormone Sensitive LipaseLipid SynthesisBiochemistry +13

Protection against post-ischemic behavioral pathology by the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) antagonist 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(f)quinoxaline (NBQX) in the gerbil

Martin E. Judge, Malcolm J. Sheardown, Poul Jacobsen, +1

Neuroscience Letters

Molecular Pharmacologyα-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic AcidMedicineBehavioural PharmacologyBehavioral Pharmacology +7

4,5,6,7-Tetrahydroisothiazolo[5,4-c]pyridin-3-ol and related analogs of THIP. Synthesis and biological activity

Povl Krogsgaard‐Larsen, Hans Mikkelsen, Poul Jacobsen, +4

Journal of Medicinal Chemistry

Synthesis and estrogen receptor binding affinities of novel pyrrolo[2,1,5-cd]indolizine derivatives

Anker Jørgensen, Poul Jacobsen, L. Christiansen, +5

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryDerivativesBiochemistryNatural SciencesMedicine +6