Allen Lovey

9-Cis retinoic acid stereoisomer binds and activates the nuclear receptor RXRα

Arthur A. Levin, Laurie J. Sturzenbecker, Sonja Kazmer et al. · Nature · 1992 · 1.2K citations

Nuclear Receptor Rxrα, Signal Transduction, Molecular Physiology +8

Retinoic acid receptors and retinoid X receptors: interactions with endogenous retinoic acids.

Gary Allenby, M. T. Bocquel, Michael A. Saunders et al. · Proceedings of the National Academy of Sciences · 1993 · 757 citations · Full text

Molecular Pharmacology, Photoreceptor Cell, Signal Transduction +15

Discovery of RG7112: A Small-Molecule MDM2 Inhibitor in Clinical Development

Binh Thanh Vu, Peter M. Wovkulich, Giacomo Pizzolato et al. · ACS Medicinal Chemistry Letters · 2013 · 373 citations · Full text

Drug Target, Cell Death, Small-molecule Mdm2 Inhibitor +17

Synthetic applications and mechanism studies of the decarbalkoxylations of geminal diesters and related systems effected in dimethyl sulfoxide by water and/or by water with added salts

A. Paul Krapcho, John F. Weimaster, J. M. ELDRIDGE et al. · The Journal of Organic Chemistry · 1978 · 256 citations

Chemical Engineering, Dimethyl Sulfoxide, Engineering +14

Activation of the p53 pathway by small-molecule-induced MDM2 and MDMX dimerization

Bradford Graves, Thelma Thompson, Mingxuan Xia et al. · Proceedings of the National Academy of Sciences · 2012 · 223 citations · Full text

Dimeric Protein Complexes, Molecular Biology, Mdmx Dimerization +16