John J. O'Shea

Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2

James A. Johnston, Masaru Kawamura, Robert A. Kirken et al. · Nature · 1994 · 595 citations · Full text

Inflammation, Cytokine, Signal Transduction +13

Unexpected Effects of FERM Domain Mutations on Catalytic Activity of Jak3

Yongjie Zhou, Min Chen, Nancy Cusack et al. · Molecular Cell · 2001 · 138 citations · Full text

Ferm Domain Mutations, Biochemistry, Unexpected Effects +4

Signaling via IL-2 and IL-4 in JAK3-Deficient Severe Combined Immunodeficiency Lymphocytes: JAK3-Dependent and Independent Pathways

Scott A. Oakes, Fabio Candotti, James A. Johnston et al. · Immunity · 1996 · 128 citations · Full text

Primary Immunodeficiency, Cytokine, Autoimmune Disease +12

Genomic Sequence, Organization, and Chromosomal Localization of HumanJAK3

M.C. Riedy, Amalia S. Dutra, Trevor Blake et al. · Genomics · 1996 · 55 citations · Full text

Chromatin, Genetics, Genomic Sequence +2

Interleukin-4 Signaling in B Lymphocytes from Patients with X-linked Severe Combined Immunodeficiency

Naomi Taylor, Fabio Candotti, Susan M. Smith et al. · Journal of Biological Chemistry · 1997 · 31 citations · Full text