Kazuhisa Tsuruta

Effect of a Recombinant Human Soluble Thrombomodulin on Mortality in Patients With Sepsis-Associated Coagulopathy

Jean‐Louis Vincent, Bruno François, Mradul Kumar Daga et al. · JAMA · 2019 · 348 citations · Full text

A Randomized, Double-Blind, Placebo-Controlled, Phase 2b Study to Evaluate the Safety and Efficacy of Recombinant Human Soluble Thrombomodulin, ART-123, in Patients With Sepsis and Suspected Disseminated Intravascular Coagulation*

Jean‐Louis Vincent, M Ramesh, David Ernest et al. · Critical Care Medicine · 2013 · 315 citations

Phase I study of a novel recombinant human soluble thrombomodulin, ART‐123

Stephan Moll, Celeste Lindley, S Pescatore et al. · Journal of Thrombosis and Haemostasis · 2004 · 72 citations · Full text

Thrombosis, Translational Medicine, Blood Platelet +8

Pharmacokinetics and Safety of a Novel Recombinant Soluble Human Thrombomodulin, ART‐123, in Healthy Male Volunteers

Mitsuyoshi Nakashima, Mitsutaka Kanamaru, Kazuo Umemura et al. · The Journal of Clinical Pharmacology · 1998 · 48 citations

Thrombin Generation Mediators and Markers in Sepsis-Associated Coagulopathy and Their Modulation by Recombinant Thrombomodulin

Debra Hoppensteadt, Kazuhisa Tsuruta, Josephine Cunanan et al. · Clinical and Applied Thrombosis/Hemostasis · 2013 · 38 citations

Severe Sepsis, Immunology, Thrombin-antithrombin Complex +19