KRP-203, a Novel Synthetic Immunosuppressant, Prolongs Graft Survival and Attenuates Chronic Rejection in Rat Skin and Heart Allografts

Hisashi Shimizu, Masafumi Takahashi, Takashi Kaneko, +13

Circulation

The <i>datA</i> locus predominantly contributes to the initiator titration mechanism in the control of replication initiation in <i>Escherichia coli</i>

Tohru Ogawa, Yoshitaka Yamada, Takao Kuroda, +2

Molecular Microbiology

Phosphodiesterase inhibitors. Part 3: Design, synthesis and structure–activity relationships of dual PDE3/4-inhibitory fused bicyclic heteroaromatic-dihydropyridazinones with anti-inflammatory and bronchodilatory activity

Koji Ochiai, Satoshi Takita, Tomohiko Eiraku, +9

Bioorganic & Medicinal Chemistry

Molecular PharmacologyMedicinal ChemistryPharmaceutical ChemistryBiochemistryMedicine +7

Phosphodiesterase inhibitors. Part 5: Hybrid PDE3/4 inhibitors as dual bronchorelaxant/anti-inflammatory agents for inhaled administration

Koji Ochiai, Satoshi Takita, Akihiko Kojima, +8

Bioorganic & Medicinal Chemistry Letters

AsthmaAntifibrotic TherapyInflammatory Lung DiseaseLung InflammationMedicine +9

Phosphodiesterase inhibitors. Part 6: Design, synthesis, and structure–activity relationships of PDE4-inhibitory pyrazolo[1,5-a]pyridines with anti-inflammatory activity

Akihiko Kojima, Satoshi Takita, Tatsunobu Sumiya, +7

Bioorganic & Medicinal Chemistry Letters

Molecular PharmacologyBiochemistryMedicinePhosphodiesterase InhibitorsRational Drug Design +6

Phosphodiesterase inhibitors. Part 2: Design, synthesis, and structure–activity relationships of dual PDE3/4-inhibitory pyrazolo[1,5-a]pyridines with anti-inflammatory and bronchodilatory activity

Koji Ochiai, N Ando, Kazuhiko Iwase, +7

Bioorganic & Medicinal Chemistry Letters

Molecular PharmacologyMedicinal ChemistryBiochemistryMedicineNatural Sciences +10

Phosphodiesterase inhibitors. Part 4: Design, synthesis and structure-activity relationships of dual PDE3/4-inhibitory fused bicyclic heteroaromatic-4,4-dimethylpyrazolones

Koji Ochiai, Satoshi Takita, Akihiko Kojima, +9

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryPharmaceutical ChemistryBiochemistryMedicineNatural Sciences +7

Nutritional Responses of Tumor‐bearing Rats to Oral or Intravenous Feeding

Tetsuya Kishi, Yasuo Iwasawa, Hiroshi Itoh, +1

Journal of Parenteral and Enteral Nutrition

NutritionFood IntakePathologyExperimental NutritionBody Composition +17

Effect of Dietary Amino Acids on Amino Acidcatabolizing Enzymes in Rat Liver

Kiwao Nakano, Tetsuya Kishi, Nobuyuki Kurita, +1

Journal of Nutrition

NutritionNutrient PhysiologyHepatologyBiochemistryAnimal Nutrition +10

Evaluation of an Infusion Solution Enriched with Branched Chain Amino Acid in Parenteral Nutrition of Rats

Tetsuya Kishi, Yasuo Iwasawa, Hiroshi Itoh, +1

Journal of Nutrition

NutritionNutrient PhysiologyInfusion Solution EnrichedMedicinePhysiology +5