René R. P. de Vries

Refining the complex rheumatoid arthritis phenotype based on specificity of the HLA–DRB1 shared epitope for antibodies to citrullinated proteins

T. Huizinga, Christopher I. Amos, Annette H M van der Helm–van Mil et al. · Arthritis & Rheumatism · 2005 · 589 citations

Life Sciences, Clinical Sciences, Immunology +17

Expression of FOXP3 mRNA is not confined to CD4+CD25+ T regulatory cells in humans

Mary E. Morgan, Jolanda van Bilsen, Aleida M. Bakker et al. · Human Immunology · 2004 · 412 citations

Life Sciences, Immunology, Molecular Biology +13

Association between HLA class II genes and autoantibodies to cyclic citrullinated peptides (CCPs) influences the severity of rheumatoid arthritis

Floris A. van Gaalen, Jill van Aken, T. Huizinga et al. · Arthritis & Rheumatism · 2004 · 394 citations · Full text

Life Sciences, Clinical Sciences, Immunology +17

Effective treatment of collagen‐induced arthritis by adoptive transfer of CD25+ regulatory T cells

Mary E. Morgan, Roelof Flierman, Leonie M. van Duivenvoorde et al. · Arthritis & Rheumatism · 2005 · 378 citations

Life Sciences, Immunology, Pathology +17

The HLA–DRB1 shared epitope alleles are primarily a risk factor for anti–cyclic citrullinated peptide antibodies and are not an independent risk factor for development of rheumatoid arthritis

Annette H M van der Helm–van Mil, K. N. Verpoort, Ferdinand C. Breedveld et al. · Arthritis & Rheumatism · 2006 · 349 citations

Life Sciences, Immunology, Internal Medicine +15