Rik de Greef

The Pharmacokinetics of Fondaparinux Sodium in Healthy Volunteers

Fran ois Donat, J Duret, Alix Santoni et al. · Clinical Pharmacokinetics · 2002 · 203 citations

Fondaparinux Sodium, Medicine, Clinical Pharmacology +3

Model-Based Characterization of the Pharmacokinetics of Pembrolizumab: A Humanized Anti-PD-1 Monoclonal Antibody in Advanced Solid Tumors

Malidi Ahamadi, Tomoko Freshwater, Marita Prohn et al. · CPT Pharmacometrics & Systems Pharmacology · 2016 · 147 citations · Full text

Pembrolizumab Clearance, Immunology, Metronomic Chemotherapy +18

Population pharmacokinetics and exposure‐response of osimertinib in patients with non‐small cell lung cancer

Kathryn H. Brown, Craig Comisar, Han Witjes et al. · British Journal of Clinical Pharmacology · 2016 · 141 citations · Full text

Time dependent pharmacokinetics of pembrolizumab in patients with solid tumor and its correlation with best overall response

Hongshan Li, Jingyu Yu, Chao Liu et al. · Journal of Pharmacokinetics and Pharmacodynamics · 2017 · 135 citations

Medicine, Pharmacology, Time Dependent Pharmacokinetics +8

Translational Pharmacokinetic/Pharmacodynamic Modeling of Tumor Growth Inhibition Supports Dose-Range Selection of the Anti-PD-1 Antibody Pembrolizumab

Andreas Lindauer, CR Valiathan, Khamir Mehta et al. · CPT Pharmacometrics & Systems Pharmacology · 2016 · 117 citations · Full text

Immunology, Pharmacotherapy, Immunotherapy +20