Ciltacabtagene autoleucel, a B-cell maturation antigen-directed chimeric antigen receptor T-cell therapy in patients with relapsed or refractory multiple myeloma (CARTITUDE-1): a phase 1b/2 open-label study

Jesús G. Berdeja, Deepu Madduri, Saad Z. Usmani, +32

The Lancet

Hematological MalignancyCell TherapyImmunotherapyCiltacabtagene AutoleucelMedicine +9

Bortezomib, thalidomide, and dexamethasone with or without daratumumab before and after autologous stem-cell transplantation for newly diagnosed multiple myeloma (CASSIOPEIA): a randomised, open-label, phase 3 study

Philippe Moreau, Michel Attal, Cyrille Hulin, +55

The Lancet

Hematological MalignancyRadiation OncologyMedicineImmunologyHematology +7

Randomized Phase III Study of Pegylated Liposomal Doxorubicin Plus Bortezomib Compared With Bortezomib Alone in Relapsed or Refractory Multiple Myeloma: Combination Therapy Improves Time to Progression

Robert Z. Orlowski, Arnon Nagler, Pieter Sonneveld, +15

Journal of Clinical Oncology

Daratumumab-Based Treatment for Immunoglobulin Light-Chain Amyloidosis

Efstathios Kastritis, Giovanni Palladini, Monique C. Minnema, +45

New England Journal of Medicine

Randomized Phase III Trial of Ibrutinib and Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone in Non–Germinal Center B-Cell Diffuse Large B-Cell Lymphoma

Anas Younes, Laurie H. Sehn, Peter Johnson, +27

Journal of Clinical Oncology

Inhibition of prostate cancer metastasis in vivo: a comparison of 1,23-dihydroxyvitamin D (calcitriol) and EB1089.

Bal L. Lokeshwar, Gary G. Schwartz, Marie G. Selzer, +4

PubMed

Steroid MetabolismUrologyChemoprevention StrategyTumor VolumesMedicine +13

Results from CARTITUDE-1: A Phase 1b/2 Study of JNJ-4528, a CAR-T Cell Therapy Directed Against B-Cell Maturation Antigen (BCMA), in Patients with Relapsed and/or Refractory Multiple Myeloma (R/R MM)

Deepu Madduri, Saad Z. Usmani, Sundar Jagannath, +12

Blood

Pegylated Liposomal Doxorubicin Plus Docetaxel Significantly Improves Time to Progression Without Additive Cardiotoxicity Compared With Docetaxel Monotherapy in Patients With Advanced Breast Cancer Previously Treated With Neoadjuvant-Adjuvant Anthracycline Therapy: Results From a Randomized Phase III Study

Joseph A. Sparano, Semiglazov Vf, Sergei Tjulandin, +10

Journal of Clinical Oncology

CARTITUDE-1: Phase 1b/2 Study of Ciltacabtagene Autoleucel, a B-Cell Maturation Antigen-Directed Chimeric Antigen Receptor T Cell Therapy, in Relapsed/Refractory Multiple Myeloma

Deepu Madduri, Jesús G. Berdeja, Saad Z. Usmani, +32

Blood

A Phase I clinical trial of ixabepilone (BMS‐247550), an epothilone B analog, administered intravenously on a daily schedule for 3 days

Sen Hong Zhuang, Manish Agrawal, Maureen Edgerly, +7

Cancer