Smitha P.S. Pillai

An aged immune system drives senescence and ageing of solid organs

Matthew J. Yousefzadeh, Rafael R. Flores, Yi Zhu et al. · Nature · 2021 · 881 citations · Full text

Inflammation, Autoimmune Disease, Anti-aging +11

In situ programming of leukaemia-specific T cells using synthetic DNA nanocarriers

Tyrel T. Smith, Sirkka B. Stephan, Howell Moffett et al. · Nature Nanotechnology · 2017 · 716 citations · Full text

Cell-based Drug Delivery, Nanomedicine, Dna Nanotechnology +13

Biopolymers codelivering engineered T cells and STING agonists can eliminate heterogeneous tumors

Tyrel T. Smith, Howell Moffett, Sirkka B. Stephan et al. · Journal of Clinical Investigation · 2017 · 329 citations · Full text

Engineering, Immunology, Immunoediting +23

Immunogenic Chemotherapy Enhances Recruitment of CAR-T Cells to Lung Tumors and Improves Antitumor Efficacy when Combined with Checkpoint Blockade

Shivani Srivastava, Scott N. Furlan, Carla A. Jaeger-Ruckstuhl et al. · Cancer Cell · 2020 · 316 citations · Full text

Lung Tumors, Tumor Immunology, Cancer Immunosurveillance +11

<i>Crebbp</i> Loss Drives Small Cell Lung Cancer and Increases Sensitivity to HDAC Inhibition

Deshui Jia, Arnaud Augert, Dong Wook Kim et al. · Cancer Discovery · 2018 · 204 citations · Full text