Jon P. Durkin

cIAP1 and cIAP2 Facilitate Cancer Cell Survival by Functioning as E3 Ligases that Promote RIP1 Ubiquitination

Mathieu J.M. Bertrand, Snezana Milutinovic, Kathleen M. Dickson et al. · Molecular Cell · 2008 · 1.1K citations

Tumor Biology, Cell Regulation, Medicine +8

Antisense oligonucleotides targeting XIAP induce apoptosis and enhance chemotherapeutic activity against human lung cancer cells in vitro and in vivo.

Yanping Hu, Gabriele Cherton-Horvat, Visia Dragowska et al. · PubMed · 2003 · 220 citations

Tumor Biology, Drug Targeting, Oncogenic Agent +15

Loss of XIAP protein expression by RNAi and antisense approaches sensitizes cancer cells to functionally diverse chemotherapeutics

Dan C. McManus, Charles Lefebvre, Gabriele Cherton-Horvat et al. · Oncogene · 2004 · 170 citations

Medicine, Xiap Protein Expression, Immunology +9

AMPA receptor-mediated regulation of a Gi-protein in cortical neurons

Yizheng Wang, Daniel L. Small, Danica Stanimirovic et al. · Nature · 1997 · 154 citations

Molecular Physiology, Neurophysiology, Ampa Receptor-mediated Regulation +6

Development of immortalized human cerebromicrovascular endothelial cell line as an in vitro model of the human blood–brain barrier

Arumugam Muruganandam, Leonie Herx, Robert Monette et al. · The FASEB Journal · 1997 · 143 citations

Cell Therapy, Engineering, Human Blood–brain Barrier +26