Michael N. Gwynn

Type IIA topoisomerase inhibition by a new class of antibacterial agents

B.D. Bax, Pan F. Chan, Drake S. Eggleston et al. · Nature · 2010 · 803 citations

Antibacterial Agents, Medicinal Chemistry, Inhibitory Activity +14

Structural basis of quinolone inhibition of type IIA topoisomerases and target-mediated resistance

Alexandre Wohlkönig, Pan F. Chan, Andrew Fosberry et al. · Nature Structural & Molecular Biology · 2010 · 301 citations

Medicinal Chemistry, Biochemistry, Natural Sciences +9

Identification, Evolution, and Essentiality of the Mevalonate Pathway for Isopentenyl Diphosphate Biosynthesis in Gram-Positive Cocci

E. Imogen Wilding, James R. Brown, Alexander P. Bryant et al. · Journal of Bacteriology · 2000 · 261 citations · Full text

Structural basis of DNA gyrase inhibition by antibacterial QPT-1, anticancer drug etoposide and moxifloxacin

Pan F. Chan, Srikannathasan Velupillai, Jianzhong Huang et al. · Nature Communications · 2015 · 153 citations · Full text

Novel Chromosomally Encoded Multidrug Efflux Transporter MdeA in <i>Staphylococcus aureus</i>

Jianzhong Huang, Paul W. O’Toole, Wei Shen et al. · Antimicrobial Agents and Chemotherapy · 2004 · 144 citations · Full text

Molecular Biology, Escherichia Coli, Antibiotic Resistance +17