P Roques

The structure of the presenilin 1 (S182) gene and identification of six novel mutations in early onset AD families

Robert Clark, M. Hutton, M. Fuldner et al. · Nature Genetics · 1995 · 476 citations · Full text

Life Sciences, Genetics, Molecular Genetics +9

PREDISPOSING LOCUS FOR ALZHEIMER'S DISEASE ON CHROMOSOME 21

AlisonM. Goate, MichaelJ. Owen, LouiseA. James et al. · The Lancet · 1989 · 267 citations

Life Sciences, Genetics, Molecular Genetics +14

Clinical comparison of Alzheimer's disease in pedigrees with the codon 717 Val→Ile mutation in the amyloid precursor protein gene

Michael Mullan, Shoji Tsuji, T. Miki et al. · Neurobiology of Aging · 1993 · 89 citations

Life Sciences, Genetics, Molecular Genetics +14

Chromosome 14 linked familial Alzheimer's disease

Angus Kennedy, Scott Newman, R. S. J. Frackowiak et al. · Brain · 1995 · 86 citations

Medicine, Neurology, Neuroscience +17

Familial Alzheimer's disease A pedigree with a mis-sense mutation in the amyloid precursor protein gene (amyloid precursor protein 717 valine → glycine)

Angus Kennedy, Sarah Newman, Andrew McCaddon et al. · Brain · 1993 · 72 citations

Medicine, Neurology, Neuroscience +17