Scott A. Reines

Distinct Mechanism for Antidepressant Activity by Blockade of Central Substance P Receptors

Mark S. Kramer, Neal R. Cutler, John P. Feighner et al. · Science · 1998 · 1.1K citations

Medicine, Pharmacology, Psychiatry +17

The Oral Neurokinin-1 Antagonist Aprepitant for the Prevention of Chemotherapy-Induced Nausea and Vomiting: A Multinational, Randomized, Double-Blind, Placebo-Controlled Trial in Patients Receiving High-Dose Cisplatin—The Aprepitant Protocol 052 Study Group

Paul J. Hesketh, Steven M. Grunberg, Richard J. Gralla et al. · Journal of Clinical Oncology · 2003 · 776 citations

Medicine, Pharmacology, Pharmacotherapy +17

A Randomized, Double-Blind, Study of Rofecoxib in Patients with Mild Cognitive Impairment

Leon J. Thal, Steven H. Ferris, Louis Kirby et al. · Neuropsychopharmacology · 2005 · 396 citations

Medicine, Neurology, Pharmacotherapy +6

Lack of Efficacy of the Substance P (Neurokinin1 Receptor) Antagonist Aprepitant in the Treatment of Major Depressive Disorder

Martin B. Keller, Stuart Montgomery, William A. Ball et al. · Biological Psychiatry · 2005 · 287 citations

Medicine, Pharmacology, Psychiatry +16

Demonstration of the Efficacy and Safety of a Novel Substance P (NK1) Receptor Antagonist in Major Depression

Mark S. Kramer, Andrew Winokur, Jeffrey E. Kelsey et al. · Neuropsychopharmacology · 2003 · 259 citations

Medicine, Pharmacology, Pharmacotherapy +15