Jean‐Louis Kraus

Imino-tetrahydro-benzothiazole Derivatives as p53 Inhibitors:  Discovery of a Highly Potent in Vivo Inhibitor and Its Action Mechanism

Nicolas Pietrancosta, Anice Moumen, Rosanna Dono et al. · Journal of Medicinal Chemistry · 2006 · 110 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

Synthesis of New Covalently Bound κ-Carrageenan−AZT Conjugates with Improved Anti-HIV Activities

Patrick Vlieghe, Thierry Clerc, Christophe Pannecouque et al. · Journal of Medicinal Chemistry · 2002 · 75 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12

Synthesis and Biological Activity of Phosphonate Analogues and Geometric Isomers of the Highly Potent Phosphoantigen (<i>E</i>)-1-Hydroxy-2-methylbut-2-enyl 4-Diphosphate

Angélique Boëdec, Hélène Sicard, Jean Dessolin et al. · Journal of Medicinal Chemistry · 2008 · 66 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

New 2-bromomethyl-8-substituted-benzo[c]chromen-6-ones. Synthesis and biological properties

Cédrik Garino, Frédéric Bihel, Nicolas Pietrancosta et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 65 citations · Full text

Natural Sciences, Chemistry, Medicinal Chemistry +10

Naphthyl and Coumarinyl Biarylpiperazine Derivatives as Highly Potent Human β-Secretase Inhibitors. Design, Synthesis, and Enzymatic BACE-1 and Cell Assays

Cédrik Garino, Taisuke Tomita, Nicolas Pietrancosta et al. · Journal of Medicinal Chemistry · 2006 · 59 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15