A comprehensive genetic map of the mouse genome

William F. Dietrich, Joyce Miller, Robert Steen, +18

Nature

Knockout MouseGeneticsGenome StructureGenome AnalysisMolecular Genetics +4

High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis

Philippe Goyette, Gabrielle Boucher, Dermot Mallon, +22

Nature Genetics

HistocompatibilityChronic Inflammatory DiseasesInflammationAutoimmune DiseaseShared Role +8

The vibrator Mutation Causes Neurodegeneration via Reduced Expression of PITPα: Positional Complementation Cloning and Extragenic Suppression

Bruce A. Hamilton, Desmond Smith, Kenneth L Mueller, +10

Neuron

Extragenic SuppressionDevelopmental BiologyReduced ExpressionGenetic DisorderGenetics +8

Integrating Autoimmune Risk Loci with Gene-Expression Data Identifies Specific Pathogenic Immune Cell Subsets

Xinli Hu, Hyun Kim, Eli A. Stahl, +3

The American Journal of Human Genetics

ImmunogeneticsAutoimmune DiseaseAutoimmune Risk LociImmunologyAutoimmunity +10

A second major histocompatibility complex susceptibility locus for multiple sclerosis

Tai Wai Yeo, Philip L. De Jager, Simon G. Gregory, +27

Annals of Neurology

An Integrated Haplotype Map of the Human Major Histocompatibility Complex

Emily C. Walsh, Kristie A. Mather, S. F. Schaffner, +12

The American Journal of Human Genetics

HistocompatibilityHlaChromatinAllelic VariantHaplotype Determination +7

Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-fungal Immunity and Intestinal Inflammation

Zhifang Cao, Kara L. Conway, Robert J. W. Heath, +15

Immunity

InflammationMucosal ImmunologyPathogenesisImmunologyInnate Immune System +4

Genetic analysis of ozone-induced acute lung injury in sensitive and resistant strains of mice

Daniel R. Prows, Howard G. Shertzer, Mark J. Daly, +2

Nature Genetics

Acute Lung InjuryGenetic AnalysisAsthmaKnockout MouseInflammatory Lung Disease +10

A Homozygous Mutation in KCTD7 Links Neuronal Ceroid Lipofuscinosis to the Ubiquitin-Proteasome System

John F. Staropoli, Amel Karaa, Elaine T. Lim, +12

The American Journal of Human Genetics

Molecular NeuroscienceMedicineNatural SciencesHomozygous MutationMolecular Biology +4

Integrated Genomics of Crohn’s Disease Risk Variant Identifies a Role for CLEC12A in Antibacterial Autophagy

Jakob Begun, Kara G. Lassen, Humberto Jijon, +19

Cell Reports