Crystal Structures of Candida albicans N-Myristoyltransferase with Two Distinct Inhibitors

Satoshi Sogabe, Miyako Masubuchi, Kiyoaki Sakata, +11

Chemistry & Biology

Antifungal AgentBiochemistryNatural SciencesMolecular BiologyYeast +2

Synthesis and biological activities of benzofuran antifungal agents targeting fungal N-myristoyltransferase

Miyako Masubuchi, Hirosato Ebiike, Ken‐ichi Kawasaki, +11

Bioorganic & Medicinal Chemistry

BiosynthesisAntifungal AgentBiochemistryBenzofuran Antifungal AgentsAntifungal Agents +6

Design and synthesis of novel benzofurans as a new class of antifungal agents targeting fungal N -myristoyltransferase. Part 1

Miyako Masubuchi, Ken‐ichi Kawasaki, Hirosato Ebiike, +9

Bioorganic & Medicinal Chemistry Letters

BiosynthesisBioorganic ChemistryPart 1EngineeringAntifungal Agent +9

Design and synthesis of novel benzofurans as a new class of antifungal agents targeting fungal N-myristoyltransferase. Part 3

Ken‐ichi Kawasaki, Miyako Masubuchi, Kenji Morikami, +12

Bioorganic & Medicinal Chemistry Letters

BiosynthesisBioorganic ChemistryEngineeringAntifungal AgentAntifungal Agents +9

Design and synthesis of novel benzofurans as a new class of antifungal agents targeting fungal N-myristoyltransferase. Part 2

Hirosato Ebiike, Miyako Masubuchi, Pingli Liu, +11

Bioorganic & Medicinal Chemistry Letters

BiosynthesisBioorganic ChemistryEngineeringAntifungal AgentAntifungal Agents +9

Cyclothiazomycin, a novel polythiazole-containing peptide with renin inhibitory activity. Taxonomy, fermentation, isolation and physico-chemical characterization.

Masahiro Aoki, Tatsuo Ohtsuka, Masayoshi Yamada, +7

The Journal of Antibiotics

Synthesis and structure–activity relationships of novel benzofuran farnesyltransferase inhibitors

Kohsuke Asoh, Masami Kohchi, Ikumi Hyoudoh, +12

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryMedicineStructure–activity RelationshipsPharmacologyPharmaceutical Chemistry +1

Tetronothiodin, a novel cholecystokinin type-B receptor antagonist produced by Streptomyces sp. NR0489. II. Isolation, characterization and biological activities.

Tatsuo Ohtsuka, HIROMICHI KOTAKI, Noboru Nakayama, +7

The Journal of Antibiotics

A new series of natural antifungals that inhibit P450 lanosterol C-14 demethylase. I. Taxonomy, fermentation, isolation and structural elucidation.

Shoko Matsukuma, Tatsuo Ohtsuka, HIROMICHI KOTAKI, +9

The Journal of Antibiotics

Structure of cyclothiazomycin, a unique polythiazole-containing peptide with renin inhibitory activity. Part 1. Chemistry and partial structures of cyclothiazomycin

Masahiro Aoki, Tatsuo Ohtsuka, Yoshiko Itezono, +3

Tetrahedron Letters

Unique Polythiazole-containing PeptideMedicinal ChemistryPart 1Bioorganic ChemistryBiochemistry +10