Michel Eichelbaum

Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver.

Thomas Lang, Kathrin Klein, Joachim E. Fischer et al. · Pharmacogenetics · 2001 · 569 citations

Medicine, Genetics, Molecular Genetics +17

Identification of the primary gene defect at the cytochrome P450 CYP2D locus

Alan C. Gough, John S. Miles, Nigel K. Spurr et al. · Nature · 1990 · 306 citations

Life Sciences, Genetics, Molecular Genetics +12

Same incidence of adverse drug events after codeine administration irrespective of the genetically determined differences in morphine formation

Klaus Eckhardt, Shuxia Li, Susanne Ammon et al. · Pain · 1998 · 262 citations

Medicine, Pharmacology, Clinical Pharmacology +16

Antipyrine as a probe for human oxidative drug metabolism: Identification of the cytochrome P450 enzymes catalyzing 4-hydroxyantipyrine, 3-hydroxymethylantipyrine, and norantipyrine formation*

Georg Engel, Ute Hofmann, H. Heidemann et al. · Clinical Pharmacology & Therapeutics · 1996 · 176 citations

Medicine, Biochemistry, Pharmacology +17

Rapid detection of CYP2D6 null alleles by long distance-and multiplex-polymerase chain reaction

Thomas St ven, Ernst-UIrich Griese, Heyo K. Kroemer et al. · Pharmacogenetics · 1996 · 84 citations

Medicine, Genetics, Pharmacology +17