James S. Nichols

Pulmonary Hypertension as a Risk Factor for Death in Patients with Sickle Cell Disease

Mark T. Gladwin, Vandana Sachdev, Maria Jison et al. · New England Journal of Medicine · 2004 · 1.3K citations

Medicine, Cardiology, Internal Medicine +16

Lactate dehydrogenase as a biomarker of hemolysis-associated nitric oxide resistance, priapism, leg ulceration, pulmonary hypertension, and death in patients with sickle cell disease

Gregory J. Kato, Vicki McGowan, Roberto F. Machado et al. · Blood · 2005 · 649 citations · Full text

Medicine, Hematology, Clinical Biochemistry +11

Relative role of heme nitrosylation and β-cysteine 93 nitrosation in the transport and metabolism of nitric oxide by hemoglobin in the human circulation

Mark T. Gladwin, Frederick P. Ognibene, Lewis K. Pannell et al. · Proceedings of the National Academy of Sciences · 2000 · 273 citations

Life Sciences, Biochemistry, Physiology +13

Nitric oxide donor properties of hydroxyurea in patients with sickle cell disease

Mark T. Gladwin, James H. Shelhamer, Frederick P. Ognibene et al. · British Journal of Haematology · 2002 · 225 citations

Medicine, Hematology, Pharmacology +8

Levels of soluble endothelium‐derived adhesion molecules in patients with sickle cell disease are associated with pulmonary hypertension, organ dysfunction, and mortality

Gregory J. Kato, Sabrina Martyr, William C. Blackwelder et al. · British Journal of Haematology · 2005 · 200 citations · Full text

Medicine, Immunology, Immunopathology +12