Mario Chan

Repeated nebulisation of non-viral CFTR gene therapy in patients with cystic fibrosis: a randomised, double-blind, placebo-controlled, phase 2b trial

Eric W.F.W. Alton, David K Armstrong, Deborah Ashby et al. · The Lancet Respiratory Medicine · 2015 · 424 citations · Full text

Pharmacy, Molecular Medicine, Pharmacotherapy +17

Preparation for a first-in-man lentivirus trial in patients with cystic fibrosis

Eric W.F.W. Alton, Jeffrey M. Beekman, A. Christopher Boyd et al. · Thorax · 2016 · 146 citations · Full text

Pharmacy, Molecular Pharmaceutics, Translational Sciences +13

Toward Gene Therapy for Cystic Fibrosis Using a Lentivirus Pseudotyped With Sendai Virus Envelopes

Katsuyuki Mitomo, Uta Griesenbach, Makoto Inoue et al. · Molecular Therapy · 2010 · 132 citations · Full text

Pharmacy, Infectious Diseases, Molecular Biology +17

Assessment of F/HN-Pseudotyped Lentivirus as a Clinically Relevant Vector for Lung Gene Therapy

Uta Griesenbach, Makoto Inoue, Cuixiang Meng et al. · American Journal of Respiratory and Critical Care Medicine · 2012 · 105 citations · Full text

Pharmacy, Molecular Biology, Molecular Medicine +15

A randomised, double-blind, placebo-controlled trial of repeated nebulisation of non-viral cystic fibrosis transmembrane conductance regulator (CFTR) gene therapy in patients with cystic fibrosis

Eric W.F.W. Alton, David K Armstrong, Deborah Ashby et al. · Efficacy and Mechanism Evaluation · 2016 · 45 citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +17