Lalith R. Jayasinghe

Efficient and practical asymmetric synthesis of the taxol C-13 side chain, N-benzoyl-(2R,3S)-3-phenylisoserine, and its analogs via chiral 3-hydroxy-4-aryl-.beta.-lactams through chiral ester enolate-imine cyclocondensation

Iwao Ojima, Ivan Habuš, Mangzhu Zhao et al. · The Journal of Organic Chemistry · 1991 · 172 citations

Natural Sciences, Chemistry, Medicinal Chemistry +9

Trioxane dimers have potent antimalarial, antiproliferative and antitumor activities in vitro

Gary H. Posner, Poonsakdi Ploypradith, Whitney Hapangama et al. · Bioorganic & Medicinal Chemistry · 1997 · 51 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +9

Stereoselective synthesis of the pyrrolizidine alkaloids (-)-integerrimine and (+)-usaramine

James D. White, John C. Amedio, Samuel Gut et al. · The Journal of Organic Chemistry · 1992 · 48 citations

Pharmacy, Chemistry, Medicinal Chemistry +9

Butitaxel Analogues:  Synthesis and Structure−Activity Relationships

Syed Mashhood Ali, Michael Z. Hoemann, Gunda I. Georg et al. · Journal of Medicinal Chemistry · 1997 · 42 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13

Novel cytotoxic 3'-(tert-Butyl) 3'-diphenyl analogs of paclitaxel and docetaxel

Syed Mashhood Ali, Michael Z. Hoemann, Jeffrey Aubé et al. · Journal of Medicinal Chemistry · 1995 · 41 citations

Medicine, Medicinal Chemistry, Pharmacology +9