Allison C. Brooke

The effects of the TRPV1 antagonist SB-705498 on TRPV1 receptor-mediated activity and inflammatory hyperalgesia in humans

Boris A. Chizh, M. O'Donnell, Antonella Napolitano et al. · Pain · 2007 · 249 citations

Medicine, Pharmacology, Pain Medicine +5

Effects of the mu-opioid receptor antagonist GSK1521498 on hedonic and consummatory eating behaviour: a proof of mechanism study in binge-eating obese subjects

Hisham Ziauddeen, Samuel R. Chamberlain, Pradeep J. Nathan et al. · Molecular Psychiatry · 2012 · 104 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Distinct Modulatory Effects of Satiety and Sibutramine on Brain Responses to Food Images in Humans: A Double Dissociation across Hypothalamus, Amygdala, and Ventral Striatum

Paul C. Fletcher, Antonella Napolitano, Andrew Skeggs et al. · Journal of Neuroscience · 2010 · 73 citations · Full text

Medicine, Neurobiology, Neuroscience +17

Opioid Receptor Modulation of Hedonic Taste Preference and Food Intake: A Single‐Dose Safety, Pharmacokinetic, and Pharmacodynamic Investigation With GSK1521498, a Novel μ‐Opioid Receptor Inverse Agonist

Pradeep J. Nathan, Barry V. O’Neill, Mark Bush et al. · The Journal of Clinical Pharmacology · 2011 · 49 citations

Medicine, Pharmacokinetics, Pharmacology +17

Multiple‐Dose Safety, Pharmacokinetics, and Pharmacodynamics of the μ‐Opioid Receptor Inverse Agonist GSK1521498

Pradeep J. Nathan, Mark Bush, Wenli Tao et al. · The Journal of Clinical Pharmacology · 2011 · 15 citations

Medicine, Pharmacokinetics, Pharmacology +17