Hiromi Fujiwara

Synergy of IL-12 and IL-18 for IFN-γ Gene Expression: IL-12-Induced STAT4 Contributes to IFN-γ Promoter Activation by Up-Regulating the Binding Activity of IL-18-Induced Activator Protein 1

Masakiyo Nakahira, Hyun-Jong Ahn, Woong-Ryeon Park et al. · The Journal of Immunology · 2002 · 256 citations · Full text

A pivotal involvement of IFN‐' in the pathogenesis of acetaminophen‐induced acute liver injury

Yuko Ishida, Toshikazu Kondo, Tohru Ohshima et al. · The FASEB Journal · 2002 · 223 citations

Wild-type Mice, Immunology, Cell Death +18

A novel function of Valpha14+CD4+NKT cells: stimulation of IL-12 production by antigen-presenting cells in the innate immune system.

Michio Tomura, Wengong Yu, Hyun‐Jong Ahn et al. · PubMed · 1999 · 210 citations

Cd4+ Nkt Cells, Th2 Development, Lymphocyte Development +16

Enhanced induction of antitumor T-cell responses by cytotoxic T lymphocyte-associated molecule-4 blockade: the effect is manifested only at the restricted tumor-bearing stages.

Yifu Yang, Jian-Ping Zou, Jie Mu et al. · PubMed · 1997 · 197 citations

Immunology, Immunologic Mechanism, Cd4 T Cell Responses +19

Systemic administration of rIL-12 induces complete tumor regression and protective immunity: response is correlated with a striking reversal of suppressed IFN-γ production by anti-tumor T cells

Jian-Ping Zou, Norihiko Yamamoto, Tetsuya Fujii et al. · International Immunology · 1995 · 196 citations