Husseini K. Manji

A Randomized Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Major Depression

Carlos A. Zarate, Jaskaran Singh, Paul J. Carlson et al. · Archives of General Psychiatry · 2006 · 3.8K citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17

Cellular Mechanisms Underlying the Antidepressant Effects of Ketamine: Role of α-Amino-3-Hydroxy-5-Methylisoxazole-4-Propionic Acid Receptors

Sungho Maeng, Carlos A. Zarate, Jing Du et al. · Biological Psychiatry · 2007 · 1.1K citations

Medicine, Neuroscience, Pharmacology +16

A Randomized Add-on Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Bipolar Depression

Nancy Diazgranados, Lobna Ibrahim, Nancy E. Brutsché et al. · Archives of General Psychiatry · 2010 · 969 citations · Full text

Medicine, Pharmacology, Psychiatry +16

Efficacy and Safety of Flexibly Dosed Esketamine Nasal Spray Combined With a Newly Initiated Oral Antidepressant in Treatment-Resistant Depression: A Randomized Double-Blind Active-Controlled Study

Vanina Popova, Ella Daly, Madhukar H. Trivedi et al. · American Journal of Psychiatry · 2019 · 872 citations · Full text

Pharmacy, Pharmacotherapy, Psychiatry +17

Efficacy of Esketamine Nasal Spray Plus Oral Antidepressant Treatment for Relapse Prevention in Patients With Treatment-Resistant Depression

Ella Daly, Madhukar H. Trivedi, Adam Janik et al. · JAMA Psychiatry · 2019 · 759 citations · Full text

Pharmacy, Pharmacotherapy, Psychiatry +17