The ORF8 protein of SARS-CoV-2 mediates immune evasion through down-regulating MHC-Ι

Yiwen Zhang, Yingshi Chen, Yuzhuang Li, +21

Proceedings of the National Academy of Sciences

Viral PathogenesisImmunologyImmunologic MechanismViral Structural ProteinImmune System +16

Disease severity dictates SARS-CoV-2-specific neutralizing antibody responses in COVID-19

Xiangyu Chen, Zhiwei Pan, Shuai Yue, +19

Signal Transduction and Targeted Therapy

Long noncoding RNA NRON contributes to HIV-1 latency by specifically inducing tat protein degradation

Jun Li, Cancan Chen, Xiancai Ma, +9

Nature Communications

A SnoRNA-derived piRNA interacts with human interleukin-4 pre-mRNA and induces its decay in nuclear exosomes

Fudi Zhong, Nan Zhou, Kang Wu, +17

Nucleic Acids Research

Glycopeptide antibiotic teicoplanin inhibits cell entry of SARS-CoV-2 by suppressing the proteolytic activity of cathepsin L

Fei Yu, Ting Pan, Feng Huang, +23

Microbial PathogensViral DiagnosticsGlycobiologyViral PathogenesisImmunotherapeutics +17

The CD39+ HBV surface protein-targeted CAR-T and personalized tumor-reactive CD8+ T cells exhibit potent anti-HCC activity

Fan Zou, Jizhou Tan, Ting Liu, +4

Molecular Therapy

Engineered triple inhibitory receptor resistance improves anti-tumor CAR-T cell performance via CD56

Fan Zou, Lijuan Lu, Jun Liu, +11

Nature Communications

TRIM28 promotes HIV-1 latency by SUMOylating CDK9 and inhibiting P-TEFb

Xiancai Ma, Tao Yang, Yuewen Luo, +20

eLife

Human RetrovirusImmunologyAntiviral ResponseMolecular BiologyResistance Mutation (Virology) +10

IL-4 Inhibits the Biogenesis of an Epigenetically Suppressive PIWI-Interacting RNA To Upregulate CD1a Molecules on Monocytes/Dendritic Cells

Xue Zhang, Xin He, Chao Liu, +11

The Journal of Immunology

Chimeric Antigen Receptor T Cells Guided by the Single-Chain Fv of a Broadly Neutralizing Antibody Specifically and Effectively Eradicate Virus Reactivated from Latency in CD4 ⁺ T Lymphocytes Isolated from HIV-1-Infected Individuals Receiving Suppressive Combined Antiretroviral Therapy

Bingfeng Liu, Fan Zou, Lijuan Lu, +7

Journal of Virology