Yang Xu

Downregulated METTL14 accumulates BPTF that reinforces super-enhancers and distal lung metastasis via glycolytic reprogramming in renal cell carcinoma

Chuanjie Zhang, Li Chen, Yihan Liu et al. · Theranostics · 2021 · 185 citations · Full text

Discovery of biclonal origin and a novel oncogene SLC12A5 in colon cancer by single-cell sequencing

Chang Yu, Jun Yu, Xiaotian Yao et al. · Cell Research · 2014 · 126 citations · Full text

Tumor Biology, Biclonal Origin, Engineering +13

Aberrant activation of m6A demethylase FTO renders HIF2α ^low/− clear cell renal cell carcinoma sensitive to BRD9 inhibitors

Chuanjie Zhang, Lu Chen, Weijuan Lou et al. · Science Translational Medicine · 2021 · 63 citations

Development and validation of a metastasis-associated prognostic signature based on single-cell RNA-seq in clear cell renal cell carcinoma

Chuanjie Zhang, Hongchao He, Xin Hu et al. · Aging · 2019 · 54 citations · Full text

Single-cell Rna-seq, Pathology, Tumor Biology +17

Exome sequencing identifies a <i>COL14A1</i> mutation in a large Chinese pedigree with punctate palmoplantar keratoderma

Birong Guo, Xin Zhang, Gang Chen et al. · Journal of Medical Genetics · 2012 · 36 citations