Ligong Chen

A network integration approach for drug-target interaction prediction and computational drug repositioning from heterogeneous information

Yunan Luo, Xinbin Zhao, Jingtian Zhou et al. · Nature Communications · 2017 · 850 citations · Full text

Apolipoprotein E4 Causes Age- and Tau-Dependent Impairment of GABAergic Interneurons, Leading to Learning and Memory Deficits in Mice

Yaisa Andrews‐Zwilling, Nga Bien‐Ly, Qin Xu et al. · Journal of Neuroscience · 2010 · 308 citations · Full text

A deep learning framework for modeling structural features of RNA-binding protein targets

Sai Zhang, Jingtian Zhou, Hailin Hu et al. · Nucleic Acids Research · 2015 · 262 citations · Full text

Structured Prediction, Engineering, Molecular Biology +20

Effect of genetic variation in the organic cation transporter 2 on the renal elimination of metformin

Ying Chen, Shuanglian Li, Chaline Brown et al. · Pharmacogenetics and Genomics · 2009 · 240 citations · Full text

OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin

Ligong Chen, Yan Shu, Xiaomin Liang et al. · Proceedings of the National Academy of Sciences · 2014 · 234 citations · Full text