Ayşe Metìn

Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper-IgE syndrome

Yoshiyuki Minegishi, Masako Saitō, Shigeru Tsuchiya et al. · Nature · 2007 · 1K citations

Life Sciences, Genetics, Immunology +13

Lentiviral Hematopoietic Stem Cell Gene Therapy in Patients with Wiskott-Aldrich Syndrome

Alessandro Aiuti, Luca Biasco, Samantha Scaramuzza et al. · Science · 2013 · 1K citations · Full text

Medicine, Cell Biology, Hematology +16

Human Tyrosine Kinase 2 Deficiency Reveals Its Requisite Roles in Multiple Cytokine Signals Involved in Innate and Acquired Immunity

Yoshiyuki Minegishi, Masako Saitō, Tomohiro Morio et al. · Immunity · 2006 · 696 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Large deletions and point mutations involving the dedicator of cytokinesis 8 (DOCK8) in the autosomal-recessive form of hyper-IgE syndrome

Karin R. Engelhardt, Sean McGhee, Sabine Winkler et al. · Journal of Allergy and Clinical Immunology · 2009 · 525 citations · Full text

Life Sciences, Genetics, Molecular Genetics +16

Loss of Interleukin-10 Signaling and Infantile Inflammatory Bowel Disease: Implications for Diagnosis and Therapy

Daniel Kotlarz, Rita Beier, Dhaarini Murugan et al. · Gastroenterology · 2012 · 469 citations · Full text

Life Sciences, Immunology, Pathobiology +14