CD147-spike protein is a novel route for SARS-CoV-2 infection to host cells

Ke Wang, Wei Chen, Zheng Zhang, +42

Signal Transduction and Targeted Therapy

SARS-CoV-2 invades host cells via a novel route: CD147-spike protein

Ke Wang, Wei Chen, Yusen Zhou, +27

Cd147-spike ProteinViral DiagnosticsViral PathogenesisImmunologyImmunodominance +16

CD147 antibody specifically and effectively inhibits infection and cytokine storm of SARS-CoV-2 and its variants delta, alpha, beta, and gamma

Jiejie Geng, Liang Chen, Yufeng Yuan, +44

Signal Transduction and Targeted Therapy

Universal ReceptorHumoral ResponseImmunologyImmunodominanceImmunologic Mechanism +17

Inhibition of ferroptosis rescues M2 macrophages and alleviates arthritis by suppressing the HMGB1/TLR4/STAT3 axis in M1 macrophages

Zhuan Feng, Feiyang Meng, Fei Huo, +9

Redox Biology

CD147 receptor is essential for TFF3-mediated signaling regulating colorectal cancer progression

Hong‐Yong Cui, Shijie Wang, Fei Song, +21

Signal Transduction and Targeted Therapy

Safety and efficacy of meplazumab in healthy volunteers and COVID-19 patients: a randomized phase 1 and an exploratory phase 2 trial

Huijie Bian, Zhaohui Zheng, Wei Ding, +55

Signal Transduction and Targeted Therapy

Di-methylation of CD147-K234 Promotes the Progression of NSCLC by Enhancing Lactate Export

Ke Wang, Wan Huang, Ruo Chen, +14

Cell Metabolism

BiosynthesisBiochemistryLactate ExportNatural SciencesMolecular Biology +2

Discovery of Tyrosinase Inhibitors: Structure-Based Virtual Screening and Biological Evaluation

Guan Wang, Jin Li, Xiaoli Pan, +4

Pharmaceutical Fronts

Pharmaceutical ScienceDrug TargetHit IdentificationHyperpigmentation TherapyChemical Biology +16

Identification of differentially expressed genes in non-small cell lung cancer

Ke Wang, Ruo Chen, Zhuan Feng, +4

Aging

GeneticsImmunologyPathologyCancer BiologyGene Expression Profiling +17

Unraveling the Design and Discovery of c-Jun N-Terminal Kinase Inhibitors and Their Therapeutic Potential in Human Diseases

Yumeng Zhu, Shuai Wen, Min Zhao, +7

Journal of Medicinal Chemistry