Wenlin Huang

Development of an Orally Available and Central Nervous System (CNS) Penetrant <i>Toxoplasma gondii</i> Calcium-Dependent Protein Kinase 1 (<i>Tg</i>CDPK1) Inhibitor with Minimal Human Ether-a-go-go-Related Gene (hERG) Activity for the Treatment of <i>Toxoplasmosis</i>

Rama Subba Rao Vidadala, Kasey Rivas, Kayode K. Ojo et al. · Journal of Medicinal Chemistry · 2016 · 96 citations · Full text

Immunology, Pathology, Cell Death +17

P53/NRF2 mediates SIRT1's protective effect on diabetic nephropathy

Fuzhe Ma, Junduo Wu, Ziping Jiang et al. · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 2019 · 77 citations

Urology, Medicine, Diabetes +5

Novel Bumped Kinase Inhibitors Are Safe and Effective Therapeutics in the Calf Clinical Model for Cryptosporidiosis

Deborah A. Schaefer, Dana P. Betzer, Kylie D. Smith et al. · The Journal of Infectious Diseases · 2016 · 70 citations · Full text

Parasitic Disease, Antiparasitic Agent, Medicine +12

Necessity of Bumped Kinase Inhibitor Gastrointestinal Exposure in Treating Cryptosporidium Infection

Samuel L.M. Arnold, Ryan Choi, Matthew A. Hulverson et al. · The Journal of Infectious Diseases · 2017 · 59 citations · Full text

Translational Medicine, Preclinical Drug Evaluation, Cryptosporidium Infection +14

Potent and Selective Inhibitors of CDPK1 from <i>T. gondii</i> and <i>C. parvum</i> Based on a 5-Aminopyrazole-4-carboxamide Scaffold

Zhongsheng Zhang, Kayode K. Ojo, Ramasubbarao Vidadala et al. · ACS Medicinal Chemistry Letters · 2013 · 54 citations · Full text