Yang Zhao

Biopharmaceutics Applications of Physiologically Based Pharmacokinetic Absorption Modeling and Simulation in Regulatory Submissions to the U.S. Food and Drug Administration for New Drugs

Fang Wu, Heta Shah, Min Li et al. · The AAPS Journal · 2021 · 59 citations

Physiologically Based Pharmacokinetics, Pharmacokinetic Modeling, Pharmacodynamics +11

In vitro toxicological assessment of free 3-MCPD and select 3-MCPD esters on human proximal tubule HK-2 cells

Miriam E. Mossoba, Mapa S.T. Mapa, Magali Araújo et al. · Cell Biology and Toxicology · 2019 · 37 citations

Medicine, Toxicology, Anti-cancer Agent +5

Assessment of intestinal absorption/metabolism of 3-chloro-1,2-propanediol (3-MCPD) and three 3-MCPD monoesters by Caco-2 cells

Magali Araújo, Jessica Beekman, Mapa S.T. Mapa et al. · Toxicology in Vitro · 2020 · 33 citations · Full text

Utilization of a model hepatotoxic compound, diglycolic acid, to evaluate liver Organ-Chip performance and in vitro to in vivo concordance

Kirsten Eckstrum, Anneliese Striz, Martine Ferguson et al. · Food and Chemical Toxicology · 2020 · 23 citations · Full text

Evaluation of the utility of the Beta Human Liver Emulation System (BHLES) for CFSAN's regulatory toxicology program

Kirsten Eckstrum, Anneliese Striz, Martine Ferguson et al. · Food and Chemical Toxicology · 2022 · 23 citations · Full text

Toxicological Mechanism, Hepatic Disorders, Microphysiological Systems +19