Zhizhen Lü

IL-18 cleavage triggers cardiac inflammation and fibrosis upon β-adrenergic insult

Han Xiao, Hao Li, Jingjing Wang et al. · European Heart Journal · 2017 · 289 citations · Full text

Metformin attenuates cardiac fibrosis by inhibiting the TGFβ1–Smad3 signalling pathway

Han Xiao, Xiaowei Ma, Wei Feng et al. · Cardiovascular Research · 2010 · 225 citations · Full text

Metformin is a novel suppressor for transforming growth factor (TGF)-β1

Han Xiao, Jianshu Zhang, Zhonghe Xu et al. · Scientific Reports · 2016 · 94 citations · Full text

β‐Adrenergic receptors stimulate interleukin‐6 production through Epac‐dependent activation of PKCδ/p38 MAPK signalling in neonatal mouse cardiac fibroblasts

Chao Chen, Jianhai Du, Feng Wei et al. · British Journal of Pharmacology · 2011 · 63 citations · Full text

Cardiac Muscle, Heart Failure, β‐Adrenergic Receptors +22

AICAR stimulates IL-6 production via p38 MAPK in cardiac fibroblasts in adult mice: A possible role for AMPK

Jianhai Du, Ning Xu, Yao Song et al. · Biochemical and Biophysical Research Communications · 2005 · 56 citations

Inflammation, Cytokine, Signal Transduction +10