Yan Zhang

Cutting Edge: TRAF6 Mediates TLR/IL-1R Signaling–Induced Nontranscriptional Priming of the NLRP3 Inflammasome

Yue Xing, Xiaomin Yao, Hua Li et al. · The Journal of Immunology · 2017 · 170 citations

Immunology, Immune Regulation, Cell Death +18

Dual-Targeting Topotecan Liposomes Modified with Tamoxifen and Wheat Germ Agglutinin Significantly Improve Drug Transport across the Blood−Brain Barrier and Survival of Brain Tumor-Bearing Animals

Ju Du, Wan-Liang Lü, Xue Ying et al. · Molecular Pharmaceutics · 2009 · 151 citations

Glioma, Tumor Biology, Neuro-oncology +17

SARS‐CoV‐2 nucleocapsid suppresses host pyroptosis by blocking Gasdermin D cleavage

Juan Ma, Fangrui Zhu, Min Zhao et al. · The EMBO Journal · 2021 · 116 citations · Full text

Gasdermin D Cleavage, Apoptosis, Immunology +5

Acetate attenuates inflammasome activation through GPR43-mediated Ca2+-dependent NLRP3 ubiquitination

Mengda Xu, Zhengyu Jiang, Changli Wang et al. · Experimental & Molecular Medicine · 2019 · 113 citations · Full text

The orphan receptor Nur77 binds cytoplasmic LPS to activate the non-canonical NLRP3 inflammasome

Fangrui Zhu, Juan Ma, Weitao Li et al. · Immunity · 2023 · 106 citations · Full text

Protein Function, Signal Transduction, Signaling Pathway +11