The B-RafV600E inhibitor dabrafenib selectively inhibits RIP3 and alleviates acetaminophen-induced liver injury

JX Li, J-M Feng, Yinghui Wang, +8

Cell Death and Disease

ApoptosisImmunologyCell DeathPharmacotherapyCancer Biology +26

Snail and Slug collaborate on EMT and tumor metastasis through miR-101-mediated EZH2 axis in oral tongue squamous cell carcinoma

Min Zheng, Yaping Jiang, Wei Chen, +13

Oncotarget

Ginsenoside Rd ameliorates colitis by inducing p62-driven mitophagy-mediated NLRP3 inflammasome inactivation in mice

Chao Liu, Jianing Wang, Yan Yang, +11

Biochemical Pharmacology

InflammationAnti-inflammatoryImmunologyChronic InflammationCell Death +6

Systemic inflammatory response syndrome in acute‐on‐chronic liver failure: Relevance of ‘golden window’: A prospective study

Ashok Choudhury, Manoj Kumar, Barjesh Chander Sharma, +36

Journal of Gastroenterology and Hepatology

Discovery of KLS-13019, a Cannabidiol-Derived Neuroprotective Agent, with Improved Potency, Safety, and Permeability

William A. Kinney, Mark E. McDonnell, Hua Zhong, +8

ACS Medicinal Chemistry Letters

Cannabis UseMedicinal ChemistryPharmaceutical ScienceImproved PotencyBiochemistry +13

Rosmarinic acid reduces the resistance of gastric carcinoma cells to 5-fluorouracil by downregulating FOXO4-targeting miR-6785-5p

Yu Chen, Dongqing Chen, Haixia Liu, +3

Biomedicine & Pharmacotherapy

Hesperetin derivative attenuates CCl4-induced hepatic fibrosis and inflammation by Gli-1-dependent mechanisms

Xin Chen, Xiaofeng Li, Yu Chen, +8

International Immunopharmacology

InflammationGli-1-dependent MechanismsLiver FibrosisFibrosisHepatology +12

Altered patterns of association between cortical thickness and subcortical volume in patients with first episode major depressive disorder: A structural MRI study

Ke Zhao, Haiyan Liu, Rui Yan, +5

Psychiatry Research Neuroimaging

PsychiatryBrain StructureStructural Mri StudyMedicineSubcortical Ischemic Depression +11

Sox9/CXCL5 axis facilitates tumour cell growth and invasion in hepatocellular carcinoma

Zhengrong Ren, Yu Chen, Lei Shi, +5

FEBS Journal

P-glycoprotein does not reduce substrate concentration from the extracellular leaflet of the plasma membrane in living cells.

Yu Chen, Alok C Pant, Sanford M. Simon

PubMed

Proteinlipid InteractionGlycobiologyGreen Fluorescence ProteinLipid MovementCellular Physiology +21